SCHEMBL9283299

SCHEMBL9283299

CC(C)CCN(CCOc1ccc(Cc2ccccc2)cc1Cl)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.47
MCHR1 Q99705 3/20 0.43
LTB4R Q15722 2/20 0.43
LTB4R2 Q9NPC1 2/20 0.43
ATM Q13315 4/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
MAPK1 P28482 2/20 0.41
PPARG P37231 1/20 0.40
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40
SLC6A9 P48067 1/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
LPAR1 Q92633 1/20 0.38
LPAR5 Q9H1C0 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9167908 0.86 LTA4H (0.51) LTA4HLTB4RLTB4R2ATMKDM4E
SCHEMBL9163338 0.85 LTA4H (0.50) LTA4HMCHR1LTB4RLTB4R2ATM
SCHEMBL9157407 0.85 LTA4H (0.47) LTA4HMCHR1LTB4RLTB4R2ATM
SCHEMBL9160178 0.84 LTA4H (0.49) LTA4HLTB4RLTB4R2ATMKDM4E
SCHEMBL9163462 0.84 LTA4H (0.47) LTA4HMCHR1LTB4RLTB4R2ATM
SCHEMBL9163526 0.83 LTA4H (0.48) LTA4HMCHR1LTB4RLTB4R2ATM
SCHEMBL9163355 0.83 LTA4H (0.46) LTA4HMCHR1LTB4RLTB4R2ATM
SCHEMBL9158338 0.82 LTA4H (0.53) LTA4HMCHR1LTB4RLTB4R2ATM
SCHEMBL9161267 0.81 LTA4H (0.46) LTA4HLTB4RLTB4R2ATMKDM4E
SCHEMBL9158402 0.80 LTA4H (0.47) LTA4HMCHR1LTB4RLTB4R2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460472-B1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL CO (JP) 1995-03-08 EP disclosed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US disclosed
EP-0460472-A1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-11 EP disclosed