Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825480 | 0.81 | LTB4R (0.46) | FFAR1FFAR4 | |
| SCHEMBL69572 | 0.69 | RARB (0.69) | RARBRARGACACB | |
| SCHEMBL29789030 | 0.69 | RARB (0.69) | RARBRARGACACB | |
| SCHEMBL9176562 | 0.68 | FFAR1 (0.51) | FFAR1FFAR4 | |
| Hydrochloric Acid SCHEMBL5666955 | 0.67 | RARB (0.67) | RARBRARGACACB | |
| SCHEMBL7494237 | 0.66 | RARB (0.45) | FFAR1RARBRARG | |
| Hydrochloric Acid SCHEMBL7415587 | 0.65 | NPC1 (0.44) | FFAR1RARBRARG | |
| SCHEMBL20026754 | 0.65 | RARB (0.55) | RARBRARGACACB | |
| SCHEMBL20764505 | 0.64 | RARB (0.58) | RARBRARGACACB | |
| SCHEMBL1549563 | 0.64 | FFAR1 (1.00) | FFAR1FFAR4CHRM2S1PR1FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651745-A1 | NEW PYRIDINE DERIVATIVES AS LEUKCOTRIENE B 4? ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994002464-A1 | NEW PYRIDINE DERIVATIVES AS LEUKCOTRIENE B4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-02-03 | — | — | WO | disclosed |