Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10011095 | 0.80 | ALDH1A1 (0.38) | ALDH1A1CYP3A4ALOX15HSD17B10CHRM1 | |
| SCHEMBL10011571 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP3A4ALOX15HSD17B10CHRM1 | |
| Butane SCHEMBL11582063 | 0.79 | ALDH1A1 (0.34) | ALDH1A1ALOX15HSD17B10MGAMGAA | |
| Butane SCHEMBL11581921 | 0.78 | POLB (0.34) | ALDH1A1ALOX15HSD17B10CHRM1MGAM | |
| SCHEMBL10011092 | 0.77 | ALDH1A1 (0.37) | ALDH1A1CYP3A4ALOX15HSD17B10CHRM1 | |
| SCHEMBL15494145 | 0.76 | TSHR (0.31) | TSHR | |
| SCHEMBL22040635 | 0.76 | MGAM (0.46) | ALDH1A1CYP3A4ALOX15HSD17B10CHRM1 | |
| SCHEMBL4984393 | 0.76 | MGAM (0.46) | ALDH1A1CYP3A4ALOX15HSD17B10CHRM1 | |
| SCHEMBL1245715 | 0.76 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX15HSD17B10CHRM1 | |
| SCHEMBL13136942 | 0.75 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ALOX15HSD17B10CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0660840-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES. | CIBA GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994005677-A1 | PHOSPHONO SUBSTITUTED TETRAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |