Naphthalene

Naphthalene

SCHEMBL9284697

CCCCCCCCCc1ccccc1N(c1ccccc1CCCCCCCCC)c1ccccc1CCCCCCCCC.N.c1ccc2ccccc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.50
TLR8 Q9NR97 1/20 0.43
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
KCNH2 Q12809 2/20 0.42
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
OXER1 Q8TDS5 1/20 0.39
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31548024 0.93 LIPG (0.56) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL14839969 0.85 LIPG (0.46) LIPGTLR8NR1H2NR1H3
SCHEMBL27910854 0.84 LIPG (0.51) LIPGTLR8NR1H2NR1H3KCNH2
SCHEMBL28160478 0.84 LIPG (0.51) LIPGTLR8NR1H2NR1H3KCNH2
SCHEMBL7922788 0.84 LIPG (0.51) LIPGTLR8NR1H2NR1H3KCNH2
SCHEMBL31622303 0.84 LIPG (0.51) LIPGTLR8NR1H2NR1H3KCNH2
SCHEMBL6231180 0.82 TLR8 (0.42) LIPGTLR8KCNH2BIDMCL1
SCHEMBL28041959 0.82 LIPG (0.49) LIPGTLR8NR1H2NR1H3KCNH2
SCHEMBL5228295 0.82 LIPG (0.56) LIPGNR1H2NR1H3KCNH2BID
SCHEMBL5223768 0.82 LIPG (0.56) LIPGNR1H2NR1H3KCNH2BID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5456989-A Charge transport layer includes a curable product of a doped amino resin FUJI ELECTRIC CO., LTD. (JP) 1995-10-10 US disclosed