Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279764 | 0.88 | PTPN1 (0.40) | PTPN1KMT2ATSPOEGFRRAB9A | |
| SCHEMBL9286155 | 0.88 | PTPN1 (0.42) | PTPN1KMT2ATSPOEGFRRAB9A | |
| SCHEMBL9279189 | 0.85 | PTPN1 (0.38) | PTPN1KMT2ATSPOEGFRRAB9A | |
| SCHEMBL9279777 | 0.84 | HRH3 (0.43) | KMT2ARAB9ANPC1NPSR1SMN1; SMN2 | |
| SCHEMBL20370165 | 0.78 | PTPN1 (0.42) | PTPN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL114746 | 0.78 | PTPN1 (0.42) | PTPN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL20370139 | 0.78 | PTPN1 (0.45) | PTPN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL9287110 | 0.78 | EGFR (0.39) | PTPN1KMT2AEGFRALOX5LMNA | |
| SCHEMBL112843 | 0.77 | PTPN1 (0.41) | PTPN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL17692799 | 0.77 | PTPN1 (0.39) | PTPN1KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315451-B2 | Tetracycline compounds | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20120135968-A1 | Tetracycline Compounds | TETRAPHASE PHARMACEUTICALS, INC. | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135968-A1 | Tetracycline Compounds | TUBB, TUBA1C, TUBA1A | PTPN1 402/4885KMT2A 2833/4885TSPO 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.