SCHEMBL9285259

SCHEMBL9285259

C=CCOC(=O)[O-].C=CC[N+](CC=C)(CC=C)CC=C

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
TSHR P16473 2/20 0.35
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
BBOX1 O75936 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
RHOA P61586 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL28241060 0.98 CYP3A4 (0.36) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL27266183 0.84 CYP3A4 (0.43) CYP3A4TSHRMAPTCACNA1BAPBA1
Lithium Ion SCHEMBL744339 0.84
Potassium Ion SCHEMBL4803276 0.84
SCHEMBL4787194 0.84
SCHEMBL175471 0.84 CYP3A4 (0.43) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL17289283 0.84 CYP3A4 (0.43) CYP3A4TSHRMAPTCACNA1BAPBA1
SCHEMBL28829702 0.84 BBOX1 (0.41) CYP3A4TSHRMAPTCACNA1BAPBA1
Ammonia Solution, Strong SCHEMBL8852339 0.82
SCHEMBL27502025 0.81 CYP3A4 (0.38) CYP3A4TSHRMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446737-A Coating is formed by separated application polyisocyantates composition and crosslinking catalyst COVESTRO DEUTSCHLAND AG 2019-11-12 CN disclosed
CN-107531875-A Process for producing polyisocyanurate plastics having functionalized surfaces 科思创德国股份有限公司 2018-01-02 CN disclosed
CN-107531876-A Poly-isocyanurate plastics with high thermal stability 科思创德国股份有限公司 2018-01-02 CN disclosed
CN-107531874-A Polyisocyanurate polymer and method for producing polyisocyanurate polymer 科思创德国股份有限公司 2018-01-02 CN disclosed
EP-0668271-A1 Process for the preparation of isocyanurate-group containing polyisocyanates BASF Aktiengesellschaft (DE) 1995-08-23 EP disclosed