SCHEMBL9285284

SCHEMBL9285284

C=CC(N)P(=O)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9285282 0.76
SCHEMBL31335258 0.70 CYP2C19 (0.33) CYP2C19LMNA
SCHEMBL18305923 0.70 CYP2C19 (0.33) CYP2C19LMNA
SCHEMBL8387670 0.69 CYP2C19 (0.40) CYP2C19LMNA
SCHEMBL8842738 0.69
SCHEMBL5974203 0.67
SCHEMBL28668983 0.67 LAP3 (0.50) CYP2C19LMNA
SCHEMBL11587320 0.65 CYP2C19 (0.30) CYP2C19LMNA
SCHEMBL442716 0.65
Hydrochloric Acid SCHEMBL11568328 0.65 CYP2C19 (0.37) CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5420328-A Esterification with alcohol and hydrolysis AFFYMAX TECHNOLOGIES, N.V. (AN) 1995-05-30 US disclosed
US-5359115-A Reacting phosphonic monoester with dialkylazodicarboxylate, triphenylphosphine and secondary alcohol to form diester, hydrolyzing selective ester to form monoester, coupling an aminoacid to yield peptidylphosphonate AFFYMAX TECHNOLOGIES, N.V. (US) 1994-10-25 US disclosed