Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | LIG1 | P18858 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560179 | 0.82 | L3MBTL1 (0.58) | PTGDR2L3MBTL1POLBSMN1; SMN2GLA | |
| SCHEMBL8414408 | 0.82 | L3MBTL1 (0.61) | PTGDR2L3MBTL1POLBSMN1; SMN2GLA | |
| SCHEMBL29502958 | 0.82 | KDM4E (0.73) | PTGDR2L3MBTL1POLBSMN1; SMN2GLA | |
| SCHEMBL341639 | 0.82 | KDM4E (0.73) | PTGDR2L3MBTL1POLBSMN1; SMN2GLA | |
| SCHEMBL1147329 | 0.81 | CYSLTR1 (0.70) | PTGDR2HPGDCYSLTR1KMT2A | |
| SCHEMBL30383343 | 0.81 | CYSLTR1 (0.70) | PTGDR2HPGDCYSLTR1KMT2A | |
| SCHEMBL1147326 | 0.81 | CYSLTR1 (0.70) | PTGDR2HPGDCYSLTR1KMT2A | |
| SCHEMBL10592502 | 0.81 | HCRTR1 (0.58) | L3MBTL1GLAKDM4EALDH1A1HTT | |
| SCHEMBL2407251 | 0.80 | CYP3A4 (0.66) | PTGDR2L3MBTL1POLBSMN1; SMN2GLA | |
| SCHEMBL9331793 | 0.79 | L3MBTL1 (0.59) | PTGDR2L3MBTL1POLBSMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033456-A2 | REDUCING INTRAOCULAR PRESSURE USING ARYLOXY- AND ARYL-ACETIC ACIDS | TELOR OPHTHALMIC PHARMACEUTICALS, INC. (US) | 1995-12-14 | — | — | WO | disclosed |