Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20218242 | 0.78 | CYP1A2 (0.59) | CYP1A2SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL29759335 | 0.78 | CYP1A2 (0.59) | CYP1A2SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL2493976 | 0.78 | CYP1A2 (0.59) | CYP1A2SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL22806019 | 0.78 | CYP1A2 (0.59) | CYP1A2SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL16277110 | 0.69 | CYP1A2 (0.56) | CYP1A2SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL30088112 | 0.68 | CYP1A2 (0.51) | CYP1A2SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL1593682 | 0.67 | LRRK2 (0.52) | SMN1; SMN2MAPTALDH1A1CTRCNTRK1 | |
| SCHEMBL13188959 | 0.67 | TDP2 (0.64) | GAAALDH1A1TDP2NSD2ABL1 | |
| SCHEMBL16277109 | 0.67 | SMN1; SMN2 (0.47) | CYP1A2SMN1; SMN2MAPTGAAALDH1A1 | |
| SCHEMBL1185191 | 0.66 | CYP1A2 (0.49) | CYP1A2SMN1; SMN2MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995018127-A1 | AZA-4-IMINOQUINOLINES, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-06 | — | — | WO | disclosed |