Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18351061 | 0.97 | POLB (0.38) | CXCR4POLBSMN1; SMN2MEN1CHRM2 | |
| SCHEMBL40040 | 0.97 | — | — | |
| SCHEMBL14037795 | 0.95 | POLB (0.37) | CXCR4POLBSMN1; SMN2MEN1CHRM2 | |
| Hydrochloric Acid SCHEMBL18770806 | 0.95 | SMN1; SMN2 (0.37) | CXCR4POLBSMN1; SMN2SIGMAR1CHRM5 | |
| SCHEMBL13671432 | 0.89 | CXCR4 (0.34) | CXCR4POLBSMN1; SMN2MEN1CHRM2 | |
| SCHEMBL1855230 | 0.89 | CXCR4 (0.50) | CXCR4POLBSMN1; SMN2MEN1CHRM2 | |
| SCHEMBL12229434 | 0.83 | CHRM5 (0.40) | CXCR4SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL1377716 | 0.83 | — | — | |
| SCHEMBL28374092 | 0.78 | — | — | |
| SCHEMBL22883386 | 0.76 | SIGMAR1 (0.51) | SMN1; SMN2MEN1KMT2ASIGMAR1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702677-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO International B.V. (NL) | 1996-03-27 | — | — | EP | disclosed |