Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.53 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.45 |
| ▸ | MTOR | P42345 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 5/20 | 0.44 |
| ▸ | CDK8 | P49336 | 3/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927457 | 0.93 | TNIK (0.49) | ECE1TNIKPIK3CAMTORMAPK1 | |
| SCHEMBL927456 | 0.93 | TNIK (0.53) | ECE1TNIKF10PIK3CAMTOR | |
| SCHEMBL926178 | 0.91 | ECE1 (0.53) | ECE1TNIKPIK3CAMTORMAPK1 | |
| SCHEMBL926596 | 0.90 | ECE1 (0.53) | ECE1TNIKPIK3CAMTORCDK8 | |
| SCHEMBL27829308 | 0.86 | TNIK (0.46) | ECE1TNIKMAPK1NPSR1BRAF | |
| SCHEMBL926224 | 0.86 | TNIK (0.49) | ECE1TNIKBRAFCDK8 | |
| SCHEMBL926044 | 0.85 | TNIK (0.49) | ECE1TNIKPIK3CAMTORMAPK1 | |
| SCHEMBL926349 | 0.85 | ECE1 (0.49) | ECE1TNIKPIK3CAMTORMAPK1 | |
| SCHEMBL926845 | 0.84 | ECE1 (0.53) | ECE1F10MAPK1HTR1ENPSR1 | |
| SCHEMBL926382 | 0.83 | TNIK (0.53) | ECE1TNIKCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235015-B1 | AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2016-08-24 | — | — | EP | disclosed |
| US-8354425-B2 | Azabicyclic carboxamide derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2013-01-15 | — | — | US | disclosed |
| US-20110009364-A1 | AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009364-A1 | AZABICYCLIC CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | ZYX, XDH, ZFX | ECE1 3015/4885TNIK 3921/4885F10 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.