SCHEMBL928677

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL929409	0.88	ALDH1A1 (0.54)	GRM5ALDH1A1HPGDGAAMAPT
	SCHEMBL930031	0.87	GRM5 (0.47)	GRM5ALDH1A1HPGDLMNAGAA
	SCHEMBL929996	0.85	ALDH1A1 (0.49)	GRM5ALDH1A1HPGDLMNAGAA
	SCHEMBL3815452	0.85	TACR3 (0.39)	MAPTTACR3TACR1TACR2KCNH2
	SCHEMBL928485	0.84	GRM5 (0.44)	GRM5ALDH1A1HPGDLMNAGAA
	SCHEMBL928769	0.83	GRM5 (0.52)	GRM5ALDH1A1HPGDLMNAGAA
	SCHEMBL928665	0.83	GRM5 (0.44)	GRM5TACR3TACR1TACR2KCNH2
	SCHEMBL928617	0.83	TACR3 (0.44)	GRM5TACR3TACR1TACR2KCNH2
	SCHEMBL930010	0.82	GRM5 (0.40)	GRM5ALDH1A1HPGDLMNAGAA
	SCHEMBL928725	0.82	GRM5 (0.48)	GRM5ALDH1A1HPGDLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.