SCHEMBL9287287

SCHEMBL9287287

O=c1ccc2c(-c3ccc(N=C=S)cc3CO)c3ccc(O)cc3oc-2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 3/20 0.53
▸ MEN1 O00255 2/20 0.53
▸ POLB P06746 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ ATM Q13315 1/20 0.53
▸ PLEC Q15149 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.49
▸ ALPL P05186 1/20 0.46
▸ ALPI P09923 1/20 0.46
▸ ALPG P10696 1/20 0.46
▸ CA9 Q16790 12/20 0.42
▸ CA1 P00915 11/20 0.42
▸ CA2 P00918 11/20 0.42
▸ CA12 O43570 7/20 0.42
▸ CA14 Q9ULX7 3/20 0.41
▸ DNASE1L3 Q13609 1/20 0.41
▸ PRMT1 Q99873 1/20 0.41
▸ CDC25A P30304 1/20 0.39
▸ CDC25B P30305 1/20 0.39
▸ CDC25C P30307 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13974890 0.85 USP2 (0.50) USP2MEN1POLBKMT2AATM
SCHEMBL2755000 0.84 USP2 (0.68) USP2MEN1POLBKMT2AATM
SCHEMBL14452763 0.83 USP2 (0.64) USP2MEN1POLBKMT2AATM
SCHEMBL15078140 0.82 USP2 (0.50) USP2MEN1POLBKMT2AATM
SCHEMBL19372715 0.81 USP2 (0.59) USP2MEN1POLBKMT2AATM
SCHEMBL14433567 0.81 MEN1 (0.68) USP2MEN1POLBKMT2AATM
SCHEMBL16731601 0.78 USP2 (0.50) USP2MEN1POLBKMT2AATM
SCHEMBL21172087 0.74 USP2 (0.56) USP2MEN1POLBKMT2AATM
SCHEMBL12708320 0.74 MEN1 (0.68) USP2MEN1POLBKMT2AATM
SCHEMBL2608622 0.73 USP2 (0.53) USP2MEN1POLBKMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012071461-A2 METHOD OF MAKING AND USING FLUORESCENT-TAGGED NANOPARTICLES AND MICROARRAYS THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) 2012-05-31 — — WO disclosed
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