Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 15/20 | 0.63 |
| ▸ | AGTR2 | P50052 | 12/20 | 0.63 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392357 | 0.95 | AGTR1 (0.56) | AGTR1AGTR2GRM2 | |
| SCHEMBL7686322 | 0.92 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL8109564 | 0.92 | AGTR1 (0.74) | AGTR1AGTR2 | |
| SCHEMBL7684785 | 0.91 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL9288565 | 0.91 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL7679757 | 0.91 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9280852 | 0.91 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL9388695 | 0.91 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9287077 | 0.91 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9387380 | 0.91 | AGTR1 (0.63) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664802-A1 | N-ARYLHETEROARYLALKYL 1-PHENYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994008990-A1 | N-ARYLHETEROARYLALKYL 1-PHENYL-IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1994-04-28 | — | — | WO | disclosed |