SCHEMBL92875

SCHEMBL92875

NC(=O)c1ccc(Cl)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31078723 0.98 F2 (0.95)
Trifluoroacetic Acid SCHEMBL5656425 0.88 F2 (0.77)
SCHEMBL6181512 0.84 F2 (0.71)
SCHEMBL18649308 0.83
SCHEMBL9144815 0.82 F2 (0.70)
SCHEMBL76028 0.80
SCHEMBL3745752 0.80
SCHEMBL1770739 0.80
SCHEMBL17088064 0.80
SCHEMBL15525171 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500403-B Preparation method of rivaroxaban 南京法恩化学有限公司 2022-04-05 CN claimed
CN-112500403-A Preparation method of rivaroxaban 南京法恩化学有限公司 2021-03-16 CN claimed
CN-104788444-B The preparation method of razaxaban 浙江天顺生物科技有限公司 2018-11-06 CN claimed
CN-104910141-B A kind of preparation method of the chloro- N- of Rivaroxaban intermediate 5- (2- oxiranylmethyl radicals) -2- thenoyl amines 浙江天顺生物科技有限公司 2018-11-02 CN claimed
CN-107089974-A A kind of preparation method of razaxaban 辅仁药业集团有限公司 2017-08-25 CN claimed
EP-2661433-B1 INDOLE COMPOUNDS OR ANALOGUES THEREOF USEFUL FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD) NOVARTIS AG (CH) 2017-08-16 EP claimed
EP-2771327-B1 NOVEL PYRAZINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2016-11-16 EP claimed
US-9403808-B2 Pyrazine derivatives HOFFMANN-LA ROCHE INC. (US) 2016-08-02 US claimed
CN-104910141-A Preparation method for Rivaroxaban intermediate 5-chloro-N-(2-oxiranylmethyl)-2-thiophene methanamide ZHEJIANG TIANSHUN BIOTECHNOLOGY CO LTD 2015-09-16 CN claimed
CN-104788444-A Preparation method of rivaroxaban ZHEJIANG TIANSHUN BIOTECHNOLOGY CO LTD 2015-07-22 CN claimed
US-20070032529-A1 Pyrazole compounds and their use as antidiabetes agents JAPAN TOBACCO INC. (JP) 2007-02-08 US claimed
US-20040102450-A1 Substituted oxoazaheterocyclyl compounds AVENTIS PHARMACEUTICALS INC. (US) 2004-05-27 US claimed
JP-2003508353-A 2003-03-04 JP claimed
EP-1051176-A4 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARM PROD INC (US) 2002-06-12 EP claimed
EP-1208097-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS Aventis Pharmaceuticals Inc. (US) 2002-05-29 EP claimed
JP-2002501024-A 2002-01-15 JP claimed
CN-1291892-A Substituted oxoazaheterocyclyl factor Xa inhibitors AWENTIS PHARMACEUTICAL INC (US) 2001-04-18 CN claimed
WO-2001007436-A2 SUBSTITUTED OXOAZAHETEROCYCLYL COMPOUNDS AVENTIS PHARMACEUTICALS INC. (US) 2001-02-01 WO claimed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP claimed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO claimed