Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 7/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9287495 | 0.84 | GABRA1 (0.42) | GABRA1GABRB2AKR1B1KDM4E | |
| SCHEMBL28551302 | 0.82 | HIF1A (0.46) | HIF1AP4HTMGCGRP4HA1MIF | |
| SCHEMBL27806948 | 0.81 | DPP4 (0.53) | HIF1AP4HTMGCGRP4HA1MIF | |
| SCHEMBL8943287 | 0.79 | FOLH1 (0.52) | GABRA1GABRB2AKR1B1 | |
| SCHEMBL9287660 | 0.78 | P4HTM (0.51) | HIF1AP4HTMP4HA1MIFMAP4K4 | |
| SCHEMBL9289369 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2P4HTMP4HA1AKR1B1 | |
| SCHEMBL18015585 | 0.75 | P4HTM (0.50) | P4HTMP4HA1MIFMAP4K4KDM4E | |
| SCHEMBL9420298 | 0.74 | GABRA1 (0.47) | GABRA1GABRB2AKR1B1ALDH1A1 | |
| SCHEMBL170787 | 0.74 | DPP4 (0.54) | GABRA1GABRB2AKR1B1MAP4K4KDM4E | |
| SCHEMBL10432643 | 0.73 | P4HTM (0.62) | HIF1AP4HTMP4HA1MIFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336619-B1 | Optically active pyridylethanol derivatives | CHISSO CORP (JP) | 1995-02-22 | — | — | EP | disclosed |
| US-4965018-A | LIQUID CRYSTAL; HIGH TWISTABILITY, TEMPERTURE CHARACTERISTICS | CHISSO CORPORATION (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0336619-A2 | Optically active pyridylethanol derivatives | Chisso Corporation (JP) | 1989-10-11 | — | — | EP | disclosed |