Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 5/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136480 | 0.86 | AHR (0.46) | TRPA1AHRPTGER1PTGER3PTGER2 | |
| SCHEMBL9289358 | 0.84 | PTGS2 (0.57) | TRPA1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9714863 | 0.82 | AHR (0.42) | AHRPTGER1PTGER3PTGER2HSD11B1 | |
| SCHEMBL9289943 | 0.82 | CHEK1 (0.49) | TRPA1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL1515713 | 0.81 | PTGER1 (0.47) | AHRPTGER1PTGER3PTGER2HSD11B1 | |
| SCHEMBL6048560 | 0.81 | SLC6A4 (0.58) | AHRSLC6A2SLC6A4SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL6048509 | 0.80 | SLC6A4 (0.56) | AHRSLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL10058354 | 0.79 | PTGS2 (0.52) | TRPA1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL11647426 | 0.78 | PTGER1 (0.53) | TRPA1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9289984 | 0.78 | CHRM1 (0.49) | TRPA1CSNK2A2CSNK2BCSNK2A1CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135997-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A LACTAM OR BENZENESULFONAMIDE COMPOUND | BACE1, STS, APP | TRPA1 3202/4885CSNK2A2 682/4885CSNK2B 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.