SCHEMBL9288338

SCHEMBL9288338

c1ccc(-c2ccc(-n3c(-c4ccc(-n5c6ccccc6c6cc(-c7cccc8c7oc7ccccc78)ccc65)cc4)nc4ccccc43)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
ALOX5 P09917 2/20 0.42
GRIA1 P42261 1/20 0.40
CACNG8 Q8WXS5 1/20 0.40
CACNG2 Q9Y698 1/20 0.40
PTGER4 P35408 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HSP90AA1 P07900 1/20 0.39
MAPT P10636 1/20 0.39
HDAC1 Q13547 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
HDAC6 Q9UBN7 2/20 0.38
GGPS1 O95749 1/20 0.38
PTGS2 P35354 1/20 0.37
RECQL P46063 1/20 0.36
PRKDC P78527 1/20 0.36
GAA P10253 1/20 0.35
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15481564 1.00 ESR1 (0.46) ESR1ESR2ALOX5GRIA1CACNG8
SCHEMBL15481551 0.99 ESR1 (0.46) ESR1ESR2ALOX5GRIA1CACNG8
SCHEMBL9288673 0.97 ESR1 (0.45) ESR1ESR2ALOX5GRIA1CACNG8
SCHEMBL459726 0.97 ESR1 (0.44) ESR1ESR2ALOX5GRIA1CACNG8
SCHEMBL9288668 0.96 ESR1 (0.43) ESR1ESR2ALOX5GRIA1CACNG8
SCHEMBL9290143 0.95 PTGER4 (0.42) ESR1ESR2ALOX5GRIA1CACNG8
SCHEMBL9290101 0.94 PTGER4 (0.43) ESR1ESR2ALOX5GRIA1CACNG8
SCHEMBL9285747 0.94 ALOX5 (0.41) ESR1ESR2ALOX5GRIA1CACNG8
SCHEMBL9288678 0.94 ESR1 (0.41) ESR1ESR2ALOX5GRIA1CACNG8
SCHEMBL15481593 0.94 MEN1 (0.41) ESR1ESR2ALOX5GRIA1CACNG8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device BRI3BP, BRD7, CDYL ESR1 685/4885ESR2 1868/4885ALOX5 1378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.