Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | AGT | P01019 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9276944 | 0.93 | AGTR1 (0.45) | AGTR1AGTR2AGT | |
| SCHEMBL9025914 | 0.93 | AGTR1 (0.51) | AGTR1AGTR2AGT | |
| SCHEMBL9289539 | 0.91 | AGTR1 (0.45) | AGTR1AGTR2AGT | |
| SCHEMBL9276162 | 0.90 | AGTR1 (0.43) | AGTR1AGTR2AGT | |
| SCHEMBL9287978 | 0.90 | AGTR1 (0.44) | AGTR1AGTR2AGT | |
| SCHEMBL9273760 | 0.89 | AGTR1 (0.46) | AGTR1AGTR2AGT | |
| SCHEMBL9286274 | 0.89 | AGTR1 (0.43) | AGTR1AGTR2AGT | |
| SCHEMBL9279495 | 0.88 | AGT (0.44) | AGTR1AGTR2AGT | |
| SCHEMBL9025803 | 0.86 | AGTR1 (0.52) | AGTR1AGTR2AGT | |
| SCHEMBL9275390 | 0.86 | AGTR1 (0.42) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654030-A1 | IMIDAZOLE DERIVATIVES HAVING A II ANTAGONIST ACTIVITY. | LUSO FARMACO INST (IT) | 1995-05-24 | — | — | EP | disclosed |