Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9289400 | 0.79 | DRD2 (0.35) | DRD2DRD4DRD3FAAHGCK | |
| SCHEMBL9106483 | 0.74 | GCK (0.41) | DRD2DRD4DRD3FAAHGCK | |
| SCHEMBL1152072 | 0.60 | DRD3 (0.78) | DRD2DRD4DRD3 | |
| SCHEMBL9109208 | 0.58 | GCK (0.41) | GCK | |
| SCHEMBL2719856 | 0.57 | DRD3 (0.49) | DRD2DRD4DRD3BCHEGAA | |
| SCHEMBL9109153 | 0.57 | GCK (0.41) | GCK | |
| SCHEMBL12064967 | 0.56 | DRD3 (0.52) | DRD2DRD4DRD3 | |
| Fumaric Acid SCHEMBL9356787 | 0.55 | DRD3 (0.62) | DRD2DRD4DRD3BCHE | |
| SCHEMBL22637544 | 0.55 | MAPT (0.53) | GRM5 | |
| SCHEMBL16043113 | 0.55 | MAPT (0.53) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646026-A1 | NOVEL OXADIAZOLE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | Allergan, Inc. (US) | 2013-10-09 | — | — | EP | claimed |
| WO-2012074718-A1 | NOVEL OXADIAZOLE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-07 | — | — | WO | claimed |
| EP-2646026-A1 | NOVEL OXADIAZOLE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | Allergan, Inc. (US) | 2013-10-09 | — | — | EP | disclosed |
| WO-2012074718-A1 | NOVEL OXADIAZOLE DERIVATIVES AS SPHINGOSINE 1-PHOSPHATE (S1P) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-07 | — | — | WO | disclosed |