SCHEMBL9290141

SCHEMBL9290141

c1ccc(-n2c(-c3cccc(-n4c5ccccc5c5cc(-c6cccc7c6sc6ccccc67)ccc54)c3)nc3ccccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.44
ALOX5 P09917 1/20 0.42
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
HDAC1 Q13547 3/20 0.39
HDAC8 Q9BY41 3/20 0.39
HDAC6 Q9UBN7 3/20 0.39
RECQL P46063 1/20 0.38
GAA P10253 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
GRIA1 P42261 1/20 0.35
CACNG8 Q8WXS5 1/20 0.35
CACNG2 Q9Y698 1/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
POLB P06746 1/20 0.34
VCP P55072 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290154 0.98 PTGER4 (0.42) PTGER4ALOX5ESR1ESR2HDAC1
SCHEMBL9285767 0.97 PTGER4 (0.41) PTGER4ALOX5ESR1ESR2HDAC1
SCHEMBL9288596 0.97 PTGER4 (0.41) PTGER4ALOX5ESR1ESR2HDAC1
SCHEMBL9289587 0.95 ESR1 (0.43) PTGER4ALOX5ESR1ESR2HDAC1
SCHEMBL9288650 0.95 PTGER4 (0.41) PTGER4ALOX5ESR1ESR2HDAC1
SCHEMBL9290160 0.95 PTGER4 (0.41) PTGER4ALOX5ESR1ESR2HDAC1
SCHEMBL9290085 0.94 PTGER4 (0.41) PTGER4ALOX5ESR1ESR2HDAC1
SCHEMBL9288674 0.94 PTGER4 (0.44) PTGER4ALOX5ESR1ESR2HDAC1
SCHEMBL458325 0.94 ESR1 (0.44) PTGER4ALOX5ESR1ESR2HDAC1
SCHEMBL15481549 0.94 ESR2 (0.46) PTGER4ALOX5ESR1ESR2HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device BRI3BP, BRD7, CDYL PTGER4 1970/4885ALOX5 1378/4885ESR1 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.