SCHEMBL458325

SCHEMBL458325

c1ccc(-n2c(-c3ccc(-n4c5ccccc5c5cc(-c6cccc7c6sc6ccccc67)ccc54)cc3)nc3ccccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
ALOX5 P09917 1/20 0.43
PTGER4 P35408 1/20 0.43
GRIA1 P42261 1/20 0.41
CACNG8 Q8WXS5 1/20 0.41
CACNG2 Q9Y698 1/20 0.41
RECQL P46063 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
PTGS2 P35354 1/20 0.38
GAA P10253 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 5/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 2/20 0.36
MAPK1 P28482 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15481549 0.98 ESR2 (0.46) ESR1ESR2ALOX5PTGER4GRIA1
SCHEMBL15481550 0.97 ESR2 (0.46) ESR1ESR2ALOX5PTGER4GRIA1
SCHEMBL9290142 0.97 ESR2 (0.46) ESR1ESR2ALOX5PTGER4GRIA1
SCHEMBL9288314 0.96 ESR1 (0.45) ESR1ESR2ALOX5PTGER4GRIA1
SCHEMBL9289587 0.95 ESR1 (0.43) ESR1ESR2ALOX5PTGER4GRIA1
SCHEMBL9288308 0.94 ESR1 (0.41) ESR1ESR2ALOX5PTGER4GRIA1
SCHEMBL9290154 0.94 PTGER4 (0.42) ESR1ESR2ALOX5PTGER4GRIA1
SCHEMBL9290146 0.94 ALOX5 (0.42) ESR1ESR2ALOX5PTGER4GRIA1
SCHEMBL9290141 0.94 PTGER4 (0.44) ESR1ESR2ALOX5PTGER4GRIA1
SCHEMBL9288595 0.94 PTGER4 (0.42) ESR1ESR2ALOX5PTGER4GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10833282-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-11-10 US disclosed
US-10833282-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-11-10 US disclosed
US-20170288153-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-10-05 US disclosed
US-20170288153-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-10-05 US disclosed
US-20170288153-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-10-05 US disclosed
US-9735372-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-15 US disclosed
US-9735372-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-15 US disclosed
US-9735372-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-15 US disclosed
US-20150287934-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-10-08 US disclosed
US-20150287934-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-10-08 US disclosed
US-8673459-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-18 US disclosed
US-8673459-B2 Light-emitting element and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-03-18 US disclosed
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed
US-20120074390-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074390-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 US disclosed
US-20120074390-A1 Light-Emitting Element and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-29 US disclosed
WO-2012033108-A1 LIGHT-EMITTING ELEMENT AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-15 WO disclosed
WO-2012033108-A1 LIGHT-EMITTING ELEMENT AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10833282-B2 Light-emitting element and electronic device SLC39A3, SLC19A2, SLC39A14 ESR1 466/4885ESR2 325/4885ALOX5 1257/4885
US-20150287934-A1 Light-Emitting Element and Electronic Device SLC39A3, SLC19A2, SLC39A14 ESR1 466/4885ESR2 325/4885ALOX5 1257/4885
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device BRI3BP, BRD7, CDYL ESR1 685/4885ESR2 1868/4885ALOX5 1378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.