Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600933 | 0.86 | HSD17B1 (0.51) | CA12CA1CA9KAT6AHDAC3 | |
| SCHEMBL14503717 | 0.85 | CA12 (0.49) | CA12CA1CA9KAT6ALCK | |
| SCHEMBL30070953 | 0.85 | CA12 (0.49) | CA12CA1CA9KAT6ALCK | |
| SCHEMBL22804504 | 0.85 | CA12 (0.49) | CA12CA1CA9KAT6ALCK | |
| SCHEMBL29953227 | 0.83 | CA12 (0.50) | CA12CA1CA9KAT6AHDAC3 | |
| SCHEMBL14503720 | 0.82 | TTK (0.48) | CA12CA1CA9KAT6AHDAC3 | |
| SCHEMBL20067498 | 0.82 | CA12 (0.46) | CA12CA1CA9KAT6AHDAC3 | |
| SCHEMBL30216106 | 0.81 | KAT6A (0.60) | CA12CA1CA9KAT6ACYP1A2 | |
| SCHEMBL3403454 | 0.81 | KAT6A (0.60) | CA12CA1CA9KAT6ACYP1A2 | |
| SCHEMBL29652239 | 0.80 | KAT6A (0.47) | CA12CA1CA9KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670787-B1 | CYTOKINE INHIBITORS | ITHERX PHARMA INC (US) | 2012-05-30 | — | — | EP | disclosed |