SCHEMBL9290290

SCHEMBL9290290

O=C1c2cccc3cccc(c23)N1c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.72
ALDH1A1 P00352 5/20 0.50
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
RXFP1 Q9HBX9 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KMT2A Q03164 5/20 0.49
MEN1 O00255 4/20 0.49
KDM4E B2RXH2 3/20 0.47
HPGD P15428 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CASP1 P29466 2/20 0.47
MPI P34949 1/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
GAA P10253 4/20 0.46
RAB9A P51151 1/20 0.46
CES2 O00748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28839593 0.90 ALDH1A1 (0.62) PDE6DALDH1A1CA12CA9RXFP1
SCHEMBL9290287 0.86 PDE6D (0.82) PDE6DALDH1A1CA12CA9RXFP1
SCHEMBL10869116 0.86 PDE6D (0.81) PDE6DALDH1A1CA12CA9RXFP1
SCHEMBL18859112 0.85 PDE6D (0.51) PDE6DALDH1A1CA12CA9RXFP1
SCHEMBL12561294 0.83 PDE6D (0.51) PDE6DALDH1A1CA12CA9RXFP1
SCHEMBL9290364 0.82 PDE6D (0.50) PDE6DALDH1A1CA12CA9RXFP1
SCHEMBL18859228 0.81 PDE6D (0.47) PDE6DALDH1A1CA12CA9RXFP1
SCHEMBL18859108 0.81 PDE6D (0.60) PDE6DALDH1A1CA12CA9RXFP1
SCHEMBL9290379 0.80 PDE6D (0.53) PDE6DALDH1A1CA12CA9RXFP1
SCHEMBL28839555 0.80 KMT2A (0.67) ALDH1A1CA12CA9KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 PDE6D 69/4885ALDH1A1 776/4885CA12 1120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.