SCHEMBL9290341

SCHEMBL9290341

O=C1c2cccc3c(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)ccc(c23)N1CC(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 13/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
MEN1 O00255 1/20 0.42
PKM P14618 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 2/20 0.42
KDM4E B2RXH2 1/20 0.42
APAF1 O14727 1/20 0.42
GAA P10253 1/20 0.42
THRB P10828 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HTT P42858 1/20 0.40
RORC P51449 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9290384 0.90 MAPT (0.45) BRD4ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL9290316 0.85 MAPT (0.41) BRD4ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL9290458 0.84 MAPT (0.39) BRD4ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL9290350 0.84 MAPT (0.51) BRD4ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL9290417 0.84 MAPT (0.42) BRD4ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL15416662 0.84 MAPT (0.42) BRD4ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL12561339 0.84 BRD4 (0.47) BRD4ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL15398148 0.81 MEN1 (0.41) BRD4ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL9290470 0.81 KDM4E (0.44) BRD4ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL9290342 0.81 KEAP1 (0.51) BRD4ALDH1A1MAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 BRD4 3880/4885ALDH1A1 776/4885MAPT 4299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.