SCHEMBL9290352

SCHEMBL9290352

Cc1cc(C)cc(N2C(=O)c3cccc4c(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)ccc2c34)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.42
KMT2A Q03164 10/20 0.41
MEN1 O00255 9/20 0.41
USP2 O75604 7/20 0.41
KEAP1 Q14145 4/20 0.41
NFE2L2 Q16236 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALDH1A1 P00352 10/20 0.40
MAPT P10636 7/20 0.40
KDM4E B2RXH2 6/20 0.40
HTT P42858 5/20 0.40
CASP1 P29466 3/20 0.40
HBB P68871 3/20 0.40
CASP7 P55210 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 5/20 0.38
GRM5 P41594 1/20 0.37
GAA P10253 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12561366 0.90 ALDH1A1 (0.49) PDE6DKMT2AMEN1USP2KEAP1
SCHEMBL9290386 0.90 PDE6D (0.48) PDE6DKMT2AMEN1USP2KEAP1
SCHEMBL9290351 0.89 PDE6D (0.50) PDE6DKMT2AMEN1USP2KEAP1
SCHEMBL12561358 0.87 MEN1 (0.47) PDE6DKMT2AMEN1USP2KEAP1
SCHEMBL9290379 0.86 PDE6D (0.53) PDE6DKMT2AMEN1USP2KEAP1
SCHEMBL12561406 0.86 KMT2A (0.49) PDE6DKMT2AMEN1USP2KEAP1
SCHEMBL9290445 0.85 PDE6D (0.42) PDE6DKMT2AMEN1USP2KEAP1
SCHEMBL9290422 0.83 KMT2A (0.49) PDE6DKMT2AMEN1USP2KEAP1
SCHEMBL9290345 0.83 KMT2A (0.49) PDE6DKMT2AMEN1USP2KEAP1
SCHEMBL9290430 0.82 GRM5 (0.47) PDE6DKMT2AMEN1USP2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 PDE6D 69/4885KMT2A 4130/4885MEN1 3537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.