Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9290569 | 0.86 | LYN (0.39) | LYNSRCMAPTKMT2AKDM4E | |
| SCHEMBL9290639 | 0.86 | LYN (0.39) | LYNSRCMAPTKMT2AKDM4E | |
| SCHEMBL9290651 | 0.80 | NPY5R (0.44) | LYNSRCKMT2AKDM4EMEN1 | |
| SCHEMBL9290636 | 0.80 | GPR39 (0.42) | KMT2AMEN1L3MBTL1NPY5R | |
| SCHEMBL9290572 | 0.77 | KDM4E (0.43) | LYNSRCMAPTKMT2AKDM4E | |
| SCHEMBL9290644 | 0.77 | HPGD (0.42) | LYNSRCMAPTKMT2AKDM4E | |
| SCHEMBL8515531 | 0.73 | LYN (0.42) | LYNSRCMAPTKMT2AKDM4E | |
| SCHEMBL8514809 | 0.72 | SQLE (0.42) | LYNSRCMAPTKMT2AKDM4E | |
| SCHEMBL9290561 | 0.70 | NPY5R (0.45) | LMNATP53GAAHTTNPY5R | |
| SCHEMBL9290602 | 0.69 | HTT (0.36) | LYNSRCMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069428-A1 | BIPYRIDINE SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OR CONDITIONS | NOSCIRA, S.A. (ES) | 2012-05-31 | — | — | WO | disclosed |