Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9290765 | 0.86 | NPSR1 (0.34) | NPSR1 | |
| SCHEMBL1964829 | 0.82 | NPSR1 (0.40) | NPSR1PAOXSIGMAR1ALDH1A1 | |
| SCHEMBL9290792 | 0.81 | — | — | |
| SCHEMBL4574081 | 0.79 | SPHK2 (0.44) | ALDH1A1 | |
| SCHEMBL6448530 | 0.79 | ALDH1A1 (0.48) | ALDH1A1 | |
| Bromide SCHEMBL9290863 | 0.77 | HRH4 (0.50) | ALDH1A1 | |
| SCHEMBL9290902 | 0.77 | SPHK2 (0.48) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4575154 | 0.77 | SPHK2 (0.43) | ALDH1A1 | |
| Iodide SCHEMBL5325538 | 0.77 | SPHK2 (0.43) | ALDH1A1 | |
| SCHEMBL3093556 | 0.77 | SPHK2 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356895-A | Aminoguanidine derivatives; preventing food spoilage, animal aging | THE ROCKEFELLER UNIVERSITY (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0327919-B1 | METHOD AND AGENTS FOR PREVENTING STAINING OF TEETH | THE ROCKEFELLER UNIVERSITY (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5140048-A | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1992-08-18 | — | — | US | disclosed |
| US-5128122-A | Nitrogen compound | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-07 | — | — | US | disclosed |
| US-5096703-A | Administering aminoguanidine or its salts; oral rinse, tooth paste | THE ROCKEFELLER UNIVERSITY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4983604-A | Aminoguanidine derivatives | THE ROCKEFELLER UNIVERSITY (US) | 1991-01-08 | — | — | US | disclosed |
| US-4978684-A | ADMINISTERING AMINOGUANIDINE DERIVATIVE | THE ROCKEFELLER UNIVERSITY (US) | 1990-12-18 | — | — | US | disclosed |
| US-4908446-A | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1990-03-13 | — | — | US | disclosed |
| EP-0327919-A2 | Method and agents for preventing staining of teeth | THE ROCKEFELLER UNIVERSITY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0316852-A2 | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1989-05-24 | — | — | EP | disclosed |