⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17395730 | 0.64 | — | — | |
| SCHEMBL17402578 | 0.64 | — | — | |
| SCHEMBL28267988 | 0.64 | — | — | |
| SCHEMBL20074148 | 0.64 | — | — | |
| SCHEMBL3264301 | 0.60 | — | — | |
| SCHEMBL7559468 | 0.60 | — | — | |
| SCHEMBL1627388 | 0.59 | — | — | |
| SCHEMBL5549399 | 0.58 | — | — | |
| SCHEMBL23636307 | 0.57 | NOS1 (0.53) | — | |
| SCHEMBL5682903 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356895-A | Aminoguanidine derivatives; preventing food spoilage, animal aging | THE ROCKEFELLER UNIVERSITY (US) | 1994-10-18 | — | — | US | disclosed |
| US-5140048-A | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1992-08-18 | — | — | US | disclosed |
| US-5128122-A | Nitrogen compound | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-07 | — | — | US | disclosed |
| US-4983604-A | Aminoguanidine derivatives | THE ROCKEFELLER UNIVERSITY (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0316852-A2 | Inhibitors of nonenzymatic cross-linking | THE ROCKEFELLER UNIVERSITY (US) | 1989-05-24 | — | — | EP | disclosed |