Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.46 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291440 | 1.00 | S1PR1 (0.46) | S1PR1RARBRARARARGPTPN11 | |
| SCHEMBL9562139 | 1.00 | S1PR1 (0.46) | S1PR1RARBRARARARGPTPN11 | |
| SCHEMBL9291060 | 1.00 | S1PR1 (0.46) | S1PR1RARBRARARARGPTPN11 | |
| SCHEMBL9291359 | 1.00 | S1PR1 (0.46) | S1PR1RARBRARARARGPTPN11 | |
| SCHEMBL9291493 | 1.00 | S1PR1 (0.46) | S1PR1RARBRARARARGPTPN11 | |
| SCHEMBL9291318 | 1.00 | S1PR1 (0.46) | S1PR1RARBRARARARGPTPN11 | |
| SCHEMBL9291855 | 0.99 | S1PR1 (0.47) | S1PR1RARBRARARARGPTPN11 | |
| SCHEMBL9291221 | 0.97 | S1PR1 (0.49) | S1PR1RARBRARARARGPTPN11 | |
| SCHEMBL9291621 | 0.93 | S1PR1 (0.43) | S1PR1RARBRARARARGPTPN11 | |
| SCHEMBL9291311 | 0.89 | FFAR4 (0.42) | S1PR1RARBRARARARGHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356563-A | Two plate electrooptical cell | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5244597-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |