Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291621 | 0.91 | S1PR1 (0.43) | FFAR4NAAAS1PR1CYP17A1HRH3 | |
| SCHEMBL9291855 | 0.90 | S1PR1 (0.47) | S1PR1CYP17A1HRH3RARARARB | |
| SCHEMBL9291221 | 0.90 | S1PR1 (0.49) | NAAAS1PR1CYP17A1HRH3RARA | |
| SCHEMBL9291493 | 0.89 | S1PR1 (0.46) | S1PR1HRH3RARARARBRARG | |
| SCHEMBL9291279 | 0.89 | S1PR1 (0.46) | S1PR1HRH3RARARARBRARG | |
| SCHEMBL9291359 | 0.89 | S1PR1 (0.46) | S1PR1HRH3RARARARBRARG | |
| SCHEMBL9562139 | 0.89 | S1PR1 (0.46) | S1PR1HRH3RARARARBRARG | |
| SCHEMBL9291318 | 0.89 | S1PR1 (0.46) | S1PR1HRH3RARARARBRARG | |
| SCHEMBL9291440 | 0.89 | S1PR1 (0.46) | S1PR1HRH3RARARARBRARG | |
| SCHEMBL9291060 | 0.89 | S1PR1 (0.46) | S1PR1HRH3RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356563-A | Two plate electrooptical cell | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5244597-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |