Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291267 | 1.00 | RARB (0.51) | RARBNR5A1LMNACYP3A4CYP2D6 | |
| SCHEMBL9291794 | 1.00 | RARB (0.51) | RARBNR5A1LMNACYP3A4CYP2D6 | |
| SCHEMBL9291365 | 1.00 | RARB (0.51) | RARBNR5A1LMNACYP3A4CYP2D6 | |
| SCHEMBL9291238 | 0.98 | LMNA (0.49) | RARBNR5A1LMNACYP3A4CYP2D6 | |
| SCHEMBL9291683 | 0.97 | CYP3A4 (0.50) | RARBNR5A1LMNACYP3A4CYP2D6 | |
| SCHEMBL9291161 | 0.95 | NR5A1 (0.53) | NR5A1LMNARAB9AS1PR3CYP2C9 | |
| SCHEMBL9178622 | 0.95 | NR5A1 (0.53) | NR5A1LMNARAB9AS1PR3CYP2C9 | |
| SCHEMBL9291450 | 0.95 | NR5A1 (0.53) | NR5A1LMNARAB9AS1PR3CYP2C9 | |
| SCHEMBL9183214 | 0.95 | NR5A1 (0.53) | NR5A1LMNARAB9AS1PR3CYP2C9 | |
| SCHEMBL9292637 | 0.95 | NR5A1 (0.53) | NR5A1LMNARAB9AS1PR3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356563-A | Two plate electrooptical cell | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5244597-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |