SCHEMBL9293175

SCHEMBL9293175

Nc1nncc(C2CN3CCC2C3)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.49
CHRM1 P11229 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9293655 0.92 CHRM2 (0.40) CHRM2CHRM1
SCHEMBL9293584 0.82 CHRM2 (0.49) CHRM2
SCHEMBL9293370 0.81 CHRM2 (0.38) CHRM2CHRM1
SCHEMBL9293182 0.79 CHRM2 (0.40) CHRM2
SCHEMBL9293199 0.78 CHRM2 (0.40) CHRM2
SCHEMBL9293608 0.78 CHRM2 (0.40) CHRM2
SCHEMBL9293664 0.78 CHRM2 (0.40) CHRM2
SCHEMBL9293824 0.74
SCHEMBL9293807 0.73 CHRM2 (0.39) CHRM2
SCHEMBL9584936 0.72 CHRM2 (0.41) CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5324724-A Azabicyclic compounds; Alzheimer's disease treatment BEECHAM GROUP P.L.C. (GB) 1994-06-28 US claimed
EP-0594605-A1 1-AZABICYCLIC COMPOUNDS, PROCESSES AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM Beecham Group p.l.c. (GB) 1994-05-04 EP claimed
WO-1991013885-A1 1-AZABICYCLIC COMPOUNDS, PROCESSES AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1991-09-19 WO claimed
US-5324724-A Azabicyclic compounds; Alzheimer's disease treatment BEECHAM GROUP P.L.C. (GB) 1994-06-28 US disclosed