Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293584 | 0.82 | CHRM2 (0.49) | CHRM2 | |
| SCHEMBL9293175 | 0.79 | CHRM2 (0.49) | CHRM2 | |
| SCHEMBL9293199 | 0.79 | CHRM2 (0.40) | CHRM2 | |
| SCHEMBL9293664 | 0.79 | CHRM2 (0.40) | CHRM2 | |
| SCHEMBL9293370 | 0.78 | CHRM2 (0.38) | CHRM2 | |
| SCHEMBL9293824 | 0.75 | — | — | |
| SCHEMBL11268817 | 0.73 | ALDH1A1 (0.45) | — | |
| SCHEMBL9459056 | 0.72 | CHRM2 (0.47) | CHRM2 | |
| SCHEMBL9293655 | 0.72 | CHRM2 (0.40) | CHRM2 | |
| SCHEMBL9458858 | 0.72 | CHRM2 (0.47) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5324724-A | Azabicyclic compounds; Alzheimer's disease treatment | BEECHAM GROUP P.L.C. (GB) | 1994-06-28 | — | — | US | claimed |
| EP-0594605-A1 | 1-AZABICYCLIC COMPOUNDS, PROCESSES AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM | Beecham Group p.l.c. (GB) | 1994-05-04 | — | — | EP | claimed |
| WO-1991013885-A1 | 1-AZABICYCLIC COMPOUNDS, PROCESSES AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1991-09-19 | — | — | WO | claimed |
| US-5324724-A | Azabicyclic compounds; Alzheimer's disease treatment | BEECHAM GROUP P.L.C. (GB) | 1994-06-28 | — | — | US | disclosed |
| EP-0594605-A1 | 1-AZABICYCLIC COMPOUNDS, PROCESSES AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM | Beecham Group p.l.c. (GB) | 1994-05-04 | — | — | EP | disclosed |
| WO-1991013885-A1 | 1-AZABICYCLIC COMPOUNDS, PROCESSES AND PHARMACEUTICAL COMPOSITONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1991-09-19 | — | — | WO | disclosed |