SCHEMBL9293201

SCHEMBL9293201

CC(C)(CNCCN)[N+](=O)[O-]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.36
CA6 P23280 3/20 0.36
CA7 P43166 3/20 0.36
CA9 Q16790 3/20 0.36
CA14 Q9ULX7 3/20 0.36
CA5B Q9Y2D0 3/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
CA2 P00918 2/20 0.35
CA3 P07451 2/20 0.35
CA4 P22748 2/20 0.35
CA5A P35218 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CA1 P00915 1/20 0.35
ALOX15 P16050 1/20 0.35
TP53 P04637 1/20 0.35
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9814556 0.87 ALDH1A1 (0.35) ALDH1A1
SCHEMBL8713535 0.87 ALDH1A1 (0.35) ALDH1A1
SCHEMBL9292353 0.87 ALDH1A1 (0.38) TDP1ALDH1A1
SCHEMBL9814471 0.85 CHRM2 (0.34) ALDH1A1
SCHEMBL9175764 0.85 CHRM2 (0.34) ALDH1A1
SCHEMBL5872431 0.85 CHRM2 (0.34) ALDH1A1
SCHEMBL9814480 0.85 CHRM2 (0.34) ALDH1A1
SCHEMBL1279123 0.85 CHRM2 (0.34) ALDH1A1
SCHEMBL1989571 0.82 ALDH1A1 (0.41) TDP1ALDH1A1
SCHEMBL10793159 0.81 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5296632-A Continuous reduction of a hindered nitro moiety in aliphatic nitro polyamines UOP (US) 1994-03-22 US claimed
EP-0448037-B1 Polyacetal compositions containing at least one oxopiperazinyl-triazine hindered amine light stabilizer DU PONT (US) 1994-09-07 EP disclosed
US-5296632-A Continuous reduction of a hindered nitro moiety in aliphatic nitro polyamines UOP (US) 1994-03-22 US disclosed
US-5270471-A Process for making alkylated polyalkylenepolyamines by selective alkylation THE B. F. GOODRICH COMPANY (US) 1993-12-14 US disclosed
US-5189173-A ALKYLATED POLYALKYLENE POLYAMINES AND PROCESS FOR SELECTIVE ALKYLATION THE BFGOODRICH COMPANY (US) 1993-02-23 US disclosed
US-5071981-A Acetal resin stabilizers THE B. F. GOODRICH COMPANY (US) 1991-12-10 US disclosed
US-5059644-A Heat resistance, colorfastness; melt processability E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-22 US disclosed
EP-0448037-A1 Polyacetal compositions containing at least one oxopiperazinyl-triazine hindered amine light stabilizer E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-09-25 EP disclosed
EP-0447973-A2 Alkylated oxo-piperazinyl-triazine THE B.F. GOODRICH COMPANY (US) 1991-09-25 EP disclosed
US-4698446-A Synthesis of polyamines and mixture formed thereby, of diprimary polyalkylene polyamines with disubstituted N-adjacent terminal carbon atom(s) THE BF GOODRICH COMPANY (US) 1987-10-06 US disclosed