Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TOP2A | P11388 | 3/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293568 | 0.90 | DPP4 (0.55) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL9292592 | 0.87 | DPP4 (0.46) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL9603753 | 0.87 | DPP4 (0.51) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL9603754 | 0.87 | DPP4 (0.51) | DPP4CHRM2DRD1DHFRLMNA | |
| Hydrochloric Acid SCHEMBL9293399 | 0.85 | DPP4 (0.65) | DPP4CHRM2DRD1DHFRLMNA | |
| Hydrochloric Acid SCHEMBL9293405 | 0.85 | DPP4 (0.65) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL10377708 | 0.84 | DPP4 (0.66) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL11022634 | 0.84 | DPP4 (0.68) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL10377719 | 0.83 | DPP4 (0.65) | DPP4CHRM2DRD1DHFRLMNA | |
| SCHEMBL10377337 | 0.83 | DPP4 (0.65) | DPP4CHRM2DRD1DHFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342846-A | 7-substituted-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid compounds and 7-(substituted triazolyl pyrrolidin-1-yl) 4-oxoquinoline-3-carboxylic acid derivatives useful as antibacterial agents | SYNPHAR LABORATORIES, INC. (CA) | 1994-08-30 | — | — | US | disclosed |
| WO-1993024481-A1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1993-12-09 | — | — | WO | disclosed |