Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 7/20 | 0.52 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.52 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.52 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293427 | 1.00 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9293430 | 1.00 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9294108 | 0.93 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9294115 | 0.93 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9294106 | 0.93 | ABCC9 (0.52) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9294613 | 0.92 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9293842 | 0.92 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9294621 | 0.92 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9293849 | 0.92 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9293846 | 0.92 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364878-A | Antiasthmatics; urogenital disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| EP-0351720-B1 | Use of substituted 3,4-dihydro-2H-benzopyrans as medicaments against obstructive disorders of the lung | HOECHST AG (DE) | 1994-08-24 | — | — | EP | disclosed |
| EP-0560399-A1 | Use of substituted 3,4-dihydro-2H-benzopyrans as medicament against disorders of the urethra | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-15 | — | — | EP | disclosed |
| US-4999371-A | Treating Cardiovascular Disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0351720-A2 | Use of substituted 3,4-dihydro-2H-benzopyrans as medicaments against obstructive disorders of the lung | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-24 | — | — | EP | disclosed |