SCHEMBL929375

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL930025	0.89	ESR2 (0.56)	GRM5DPP4DPP9ESR2ESR1
	SCHEMBL928854	0.85	GRM5 (0.56)	GRM5ESR2ESR1ALDH1A1HPGD
	SCHEMBL3428330	0.85	ESR2 (0.44)	GRM5ESR2ESR1KMT2AALDH1A1
	SCHEMBL3820997	0.85	DPP4 (0.47)	DPP4DPP8DPP9ALDH1A1LMNA
	SCHEMBL930508	0.83	GRM5 (0.52)	GRM5ESR2ESR1KMT2AALDH1A1
	SCHEMBL929475	0.81	P2RX7 (0.56)	GRM5ESR2ESR1ALDH1A1HPGD
	SCHEMBL928278	0.81	GRM5 (0.42)	GRM5ESR2ESR1KMT2AALDH1A1
	SCHEMBL927851	0.81	GRM5 (0.51)	GRM5ALDH1A1GAAMAPTTDP1
	SCHEMBL927967	0.80	GRM5 (0.56)	GRM5ESR2ESR1ALDH1A1HPGD
	SCHEMBL928669	0.79	P2RX7 (0.49)	GRM5P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.