Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | STK3 | Q13188 | 1/20 | 0.41 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.41 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504406 | 0.88 | ANPEP (0.46) | TSHRLMNASLC1A2SLC1A1GABRR1 | |
| SCHEMBL9505565 | 0.88 | ANPEP (0.46) | TSHRLMNASLC1A2SLC1A1GABRR1 | |
| SCHEMBL9504417 | 0.88 | ANPEP (0.46) | TSHRLMNASLC1A2SLC1A1GABRR1 | |
| SCHEMBL9505616 | 0.87 | ROCK2 (0.46) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL5147855 | 0.87 | ROCK2 (0.46) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL3501685 | 0.87 | ROCK2 (0.46) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| SCHEMBL824158 | 0.83 | ACE (0.39) | ROCK2ROCK1TSHRLMNASLC1A2 | |
| SCHEMBL14436548 | 0.83 | ACE (0.39) | ROCK2ROCK1TSHRLMNASLC1A2 | |
| SCHEMBL25544633 | 0.83 | ACE (0.39) | ROCK2ROCK1TSHRLMNASLC1A2 | |
| SCHEMBL25544782 | 0.83 | ACE (0.39) | ROCK2ROCK1TSHRLMNASLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053742-A | New tricyclic compound | ABBVIE 公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108774237-A | New tricyclic compound | ABBVIE 公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-104370909-B | Tricyclic compound | ABBVIE 公司 | 2018-09-11 | — | — | CN | disclosed |
| CN-104370909-A | Novel tricyclic compounds | ABBOTT LAB | 2015-02-25 | — | — | CN | disclosed |
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| EP-0329105-B1 | MOLECULAR WEIGHT CONTROLLER FOR POLYMERIZATION OF LACTAMS TO POLYAMIDES | BASF Corporation (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5006635-A | Monofunctional amine, monofunctional acid, salt of aminoacid, polyamides | BASF CORPORATION (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0329105-A2 | Molecular weight controller for polymerization of lactams to polyamides | BASF Corporation (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4844834-A | Molecular weight controller for polymerization of lactams to polyamides | BASF CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |