Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 18/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 17/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 13/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623541 | 0.82 | MTNR1A (0.62) | ALDH1A1KDM4EHSD17B10HTTGAA | |
| SCHEMBL9293461 | 0.82 | KDM4E (0.65) | ALDH1A1KDM4EHSD17B10RXFP1HTT | |
| SCHEMBL9294138 | 0.81 | KDM4E (0.71) | ALDH1A1KDM4EHSD17B10RXFP1SMN1; SMN2 | |
| SCHEMBL9293307 | 0.79 | KDM4E (0.65) | ALDH1A1KDM4EHSD17B10RXFP1HTT | |
| SCHEMBL27576848 | 0.77 | KDM4E (0.65) | ALDH1A1KDM4EHSD17B10RXFP1SMN1; SMN2 | |
| SCHEMBL31222313 | 0.76 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10RXFP1GAA | |
| SCHEMBL31222308 | 0.76 | KDM4E (1.00) | ALDH1A1KDM4EHSD17B10RXFP1GAA | |
| SCHEMBL30705593 | 0.76 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10RXFP1HTT | |
| Hydrochloric Acid SCHEMBL9294125 | 0.75 | KDM4E (0.56) | ALDH1A1KDM4EHSD17B10RXFP1HTT | |
| SCHEMBL24852632 | 0.75 | MAPT (0.67) | ALDH1A1KDM4EHSD17B10RXFP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | disclosed |