Valine

Valine

SCHEMBL9294580

CC#N.CC(C)[C@H](N)C(=O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.75
DPP4 P27487 6/20 0.44
SLC1A3 P43003 4/20 0.41
SLC1A2 P43004 4/20 0.41
SLC1A1 P43005 4/20 0.41
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
TP53 P04637 1/20 0.35
FAP Q12884 1/20 0.34
DPP8 Q6V1X1 1/20 0.34
DPP9 Q86TI2 1/20 0.34
DPP7 Q9UHL4 1/20 0.34
LAP3 P28838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL18051147 1.00 SLC7A5 (0.75) SLC7A5DPP4SLC1A3SLC1A2SLC1A1
Valine SCHEMBL23149812 1.00 SLC7A5 (0.75) SLC7A5DPP4SLC1A3SLC1A2SLC1A1
Valine SCHEMBL28422139 1.00 SLC7A5 (0.75) SLC7A5DPP4SLC1A3SLC1A2SLC1A1
Valine SCHEMBL6295413 0.90 SLC7A5 (0.75) SLC7A5DPP4SLC1A3SLC1A2SLC1A1
Valine SCHEMBL9066603 0.90 SLC7A5 (0.75) SLC7A5DPP4SLC1A3SLC1A2SLC1A1
Valine SCHEMBL28116054 0.89
Valine SCHEMBL2217538 0.89
Valine SCHEMBL27604279 0.89 SLC7A5 (0.94) SLC7A5DPP4SLC1A3SLC1A2SLC1A1
Valine SCHEMBL6358549 0.89 SLC7A5 (0.94) SLC7A5DPP4SLC1A3SLC1A2SLC1A1
Valine SCHEMBL11014861 0.88 SLC7A5 (0.71) SLC7A5DPP4SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112595783-A Method for detecting multiple antibiotics in livestock and poultry excrement based on magnetic nanocomposite 山东省农业科学院农业质量标准与检测技术研究所 2021-04-02 CN claimed
CN-112305105-A Method for measuring content of chemical components in plums 西藏农牧学院 2021-02-02 CN claimed
CN-110511204-A The preparation method of benzyl cyanide TOPHARMAN SHANGHAI CO LTD 2019-11-29 CN claimed
CN-107045020-A A kind of method of N content of nitrosamines in complete detection meat products 广西壮族自治区食品药品检验所 2017-08-15 CN claimed
CN-118258932-A Method for determining triethanolamine in starting material SM2 of nicorandil bulk drug 重庆华邦胜凯制药有限公司 2024-06-28 CN disclosed
CN-117607285-A Method for detecting concentration of NTM (negative temperature coefficient) disease drug in blood plasma by using triple quadrupole tandem mass spectrometry 上海康黎医学检验所有限公司 2024-02-27 CN disclosed
US-20230126662-A1 SPIROCYCLIC PIPERIDINE MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF Crinetics Pharmaceuticals, Inc. 2023-04-27 US disclosed
CN-115160387-B Novel method for synthesizing compound arginine diglycoside AFG in red ginseng 吉林农业大学 2023-03-10 CN disclosed
CN-115073361-A Rosin diterpenoid compound and preparation method and application thereof 广东药科大学 2022-09-20 CN disclosed
CN-115073538-A Novel method for synthesizing compound arginine fructoside AF in ginseng 吉林农业大学 2022-09-20 CN disclosed
CN-110988163-B Method for separating and determining levocetirizine hydrochloride and genotoxic impurity E thereof by HPLC method 重庆华邦胜凯制药有限公司 2022-04-19 CN disclosed
WO-2021133563-A1 SPIROCYCLIC PIPERIDINE MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF Crinetics Pharmaceuticals, Inc. (US) 2021-07-01 WO disclosed
CN-106146332-A Separate and measure Linezolid raw material X3 and the method for process contaminants X2 thereof 重庆华邦胜凯制药有限公司 2016-11-23 CN disclosed
CN-105954419-A Method for separating and determining levocetirizine hydrochloride and enantiomer thereof through HPLC method 重庆华邦胜凯制药有限公司 2016-09-21 CN disclosed
CN-105873612-A Engineered anti-DLL 3 conjugates and methods of use 施特姆森特克斯股份有限公司 2016-08-17 CN disclosed
CN-105030687-A Medicine A317491 nanometer particle and application and preparation thereof ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV 2015-11-11 CN disclosed
CN-103705470-B Methylprednisolone-loading nanoparticles as well as preparation method and application thereof UNIV NANTONG 2015-06-17 CN disclosed
CN-103705470-A Methylprednisolone-loading nanoparticles as well as preparation method and application thereof UNIV NANTONG 2014-04-09 CN disclosed
EP-0579738-A1 IMPROVED PROCESS FOR PREPARING PHENYL ESTERS OF SUBSTITUTED ACIDS. DU PONT (US) 1994-01-26 EP disclosed
WO-1992016492-A1 IMPROVED PROCESS FOR PREPARING PHENYL ESTERS OF SUBSTITUTED ACIDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230126662-A1 SPIROCYCLIC PIPERIDINE MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF MC2R, MC1R, MC3R SLC7A5 3872/4885DPP4 1374/4885SLC1A3 2752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.