SCHEMBL9294641

SCHEMBL9294641

C=CCOC(=O)C(=C)COC(=O)CC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 1/20 0.37
GAA P10253 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
CYP3A4 P08684 1/20 0.32
CASP1 P29466 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7559435 0.84 TSHR (0.38) TDP1TSHRGAAMGAMSI
SCHEMBL29129595 0.82 TDP1 (0.49) TDP1TSHRGAAMGAMSI
SCHEMBL530348 0.82 TDP1 (0.38) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL9513 0.82 TSHR (0.50) TDP1TSHRGAAMGAMSI
SCHEMBL6578505 0.81 MGAM (0.45) TSHRGAAMGAMSIMGAM2
SCHEMBL5702374 0.80 TSHR (0.48) TDP1TSHRGAAMGAMSI
SCHEMBL1616122 0.80 TSHR (0.48) TDP1TSHRGAAMGAMSI
Acetone SCHEMBL28861611 0.80 TSHR (0.48) TDP1TSHRGAAMGAMSI
SCHEMBL5134550 0.80 TSHR (0.48) TDP1TSHRGAAMGAMSI
SCHEMBL2221470 0.80 TSHR (0.48) TDP1TSHRGAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6056746-A None JP disclosed
JP-H0656746-A PRODUCTION OF 2-@(3754/24)3-OXOBUTYL)ACRYLIC ACID ALKYL ESTER NIPPON SYNTHETIC CHEM IND CO LTD:THE 1994-03-01 JP disclosed