Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3624554 | 0.78 | PIM1 (0.43) | PIM1KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL14970142 | 0.74 | PIM1 (0.38) | PIM1KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9294083 | 0.73 | CYP1A2 (0.49) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL9627581 | 0.72 | LMNA (0.33) | SMN1; SMN2 | |
| SCHEMBL13140303 | 0.71 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL3626874 | 0.70 | PIM1 (0.38) | PIM1KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3627722 | 0.70 | PIM1 (0.38) | PIM1KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL558050 | 0.70 | PIM1 (0.38) | PIM1KDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL558692 | 0.70 | PIM1 (0.38) | PIM1KDM4EALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10220884 | 0.70 | MAPT (0.38) | PIM1KDM4EALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430471-B1 | Fungicides | ZENECA LTD (GB) | 1994-09-07 | — | — | EP | disclosed |
| US-5314892-A | Fungicidal pyrimidinyloxyphenyl-3-methoxy propenoates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-05-24 | — | — | US | disclosed |
| US-5179098-A | Substituted, methoxypropenoate pyrimidines, plants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-12 | — | — | US | disclosed |
| EP-0430471-A1 | Fungicides | ZENECA LIMITED (GB) | 1991-06-05 | — | — | EP | disclosed |