Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGT | P01019 | 2/20 | 0.68 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294985 | 1.00 | AGT (0.68) | AGTAGTR1AGTR2 | |
| SCHEMBL9384588 | 0.93 | AGT (0.66) | AGTAGTR1AGTR2 | |
| SCHEMBL9384590 | 0.93 | AGT (0.66) | AGTAGTR1AGTR2 | |
| SCHEMBL9295608 | 0.88 | AGT (0.67) | AGTAGTR1AGTR2 | |
| SCHEMBL9295694 | 0.88 | AGT (0.66) | AGTAGTR1AGTR2 | |
| SCHEMBL9311665 | 0.86 | AGT (0.69) | AGTAGTR1AGTR2 | |
| SCHEMBL9567372 | 0.86 | AGT (0.56) | AGTAGTR1AGTR2 | |
| SCHEMBL9296054 | 0.85 | AGT (0.67) | AGTAGTR1AGTR2 | |
| SCHEMBL9404590 | 0.84 | AGT (0.69) | AGTAGTR1AGTR2 | |
| SCHEMBL9295555 | 0.84 | AGT (0.69) | AGTAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621276-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolinones | AMERICAN CYANAMID COMPANY (US) | 1994-10-26 | — | — | EP | disclosed |
| US-5358951-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| US-5292734-A | Angiotensin II receptor blocking 2,3,6 substituted quinazolinones | AMERICAN CYANAMID COMPANY (US) | 1994-03-08 | — | — | US | disclosed |