Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGT | P01019 | 4/20 | 0.72 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.72 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295027 | 1.00 | AGT (0.72) | AGTAGTR1AGTR2 | |
| SCHEMBL9295706 | 1.00 | AGT (0.72) | AGTAGTR1AGTR2 | |
| SCHEMBL9295066 | 0.98 | AGT (0.74) | AGTAGTR1AGTR2 | |
| SCHEMBL9295030 | 0.98 | AGT (0.74) | AGTAGTR1AGTR2 | |
| SCHEMBL9294927 | 0.98 | AGT (0.74) | AGTAGTR1AGTR2 | |
| SCHEMBL9294944 | 0.98 | AGT (0.74) | AGTAGTR1AGTR2 | |
| SCHEMBL9295430 | 0.91 | AGT (0.64) | AGTAGTR1AGTR2 | |
| SCHEMBL9295424 | 0.91 | AGT (0.64) | AGTAGTR1AGTR2 | |
| SCHEMBL9295226 | 0.91 | AGTR1 (0.65) | AGTAGTR1AGTR2 | |
| SCHEMBL9295031 | 0.91 | AGTR1 (0.65) | AGTAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358951-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1994-10-25 | — | — | US | claimed |
| EP-0621276-A1 | Angiotensin II receptor blocking 2,3,6-substituted quinazolinones | AMERICAN CYANAMID COMPANY (US) | 1994-10-26 | — | — | EP | disclosed |
| US-5358951-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| US-5292734-A | Angiotensin II receptor blocking 2,3,6 substituted quinazolinones | AMERICAN CYANAMID COMPANY (US) | 1994-03-08 | — | — | US | disclosed |