Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 7/20 | 0.75 |
| ▸ | GSK3A | P49840 | 2/20 | 0.71 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.71 |
| ▸ | PNP | P00491 | 1/20 | 0.68 |
| ▸ | NT5E | P21589 | 1/20 | 0.67 |
| ▸ | KRAS | P01116 | 7/20 | 0.65 |
| ▸ | TGM2 | P21980 | 1/20 | 0.62 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295421 | 1.00 | HINT1 (0.75) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL2994004 | 0.90 | HINT1 (0.72) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL6065959 | 0.90 | HINT1 (0.77) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL217117 | 0.89 | HINT1 (0.80) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL5358571 | 0.88 | HINT1 (0.70) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL1611244 | 0.88 | HINT1 (0.77) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL439016 | 0.87 | HINT1 (0.78) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL3970953 | 0.87 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL3514472 | 0.87 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14PNP | |
| SCHEMBL17355882 | 0.87 | HINT1 (0.73) | HINT1GSK3ARPS6KA3MAPK14PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565646-A4 | — | — | 1994-08-03 | — | — | EP | disclosed |
| EP-0565646-A1 | NUCLEOSIDES AND OLIGONUCLEOSIDES WITH A PHOSPHATE-FREE INTERNUCLEOSIDE BACKBONE AND PROCESS FOR PREPARING THE SAME | BAYLOR COLLEGE OF MEDICINE (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5175266-A | Oxidizing hydroxymethyl function of azidodeoxynucleosides to acid in presence of ruthenium tetroxide | TRIPLEX PHARMACEUTICAL CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| WO-1992018518-A1 | NUCLEOSIDES AND OLIGONUCLEOSIDES WITH A PHOSPHATE-FREE INTERNUCLEOSIDE BACKBONE AND PROCESS FOR PREPARING THE SAME | BAYLOR COLLEGE OF MEDICINE (US) | 1992-10-29 | — | — | WO | disclosed |