Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516866 | 0.83 | ADORA2B (1.00) | ADORA2BLMNARXFP1MAPK1SMN1; SMN2 | |
| SCHEMBL12260543 | 0.82 | RXFP1 (0.69) | ADORA2BLMNARXFP1MAPK1TP53 | |
| SCHEMBL12260309 | 0.81 | ADORA2B (0.56) | ADORA2BLMNARXFP1MAPK1TP53 | |
| SCHEMBL5462777 | 0.81 | RXFP1 (0.78) | ADORA2BLMNARXFP1MAPK1TP53 | |
| SCHEMBL11205608 | 0.81 | PDE4A (0.74) | ADORA2BLMNARXFP1MAPK1SMN1; SMN2 | |
| SCHEMBL9296212 | 0.79 | ADORA2B (0.76) | ADORA2BLMNARXFP1MAPK1KMT2A | |
| SCHEMBL10967382 | 0.79 | MAPK1 (0.82) | ADORA2BLMNARXFP1MAPK1SMN1; SMN2 | |
| SCHEMBL17744968 | 0.79 | RXFP1 (0.75) | ADORA2BLMNARXFP1MAPK1TP53 | |
| SCHEMBL3860920 | 0.79 | SMN1; SMN2 (0.78) | ADORA2BLMNARXFP1MAPK1TP53 | |
| SCHEMBL18166633 | 0.78 | RXFP1 (0.56) | ADORA2BLMNARXFP1MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304645-A | Colored or fluorescent labels | BOEHRINGER MANNHEIM GMBH (DE) | 1994-04-19 | — | — | US | disclosed |
| US-4954630-A | COLORIMETRIC OR FLUORESCENT ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-09-04 | — | — | US | disclosed |
| EP-0209875-B1 | RESORUFIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Roche Diagnostics GmbH (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0209875-A1 | Resorufin derivatives and process for their preparation | Roche Diagnostics GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |