Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 2/20 | 0.71 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.70 |
| ▸ | SRC | P12931 | 2/20 | 0.70 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.70 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.70 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.70 |
| ▸ | LDHA | P00338 | 1/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.70 |
| ▸ | FBP1 | P09467 | 1/20 | 0.70 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.70 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.70 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.70 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9295615 | 1.00 | AHCY (0.71) | AHCYP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL11519682 | 0.91 | P2RY1 (0.68) | AHCYP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL30637132 | 0.91 | P2RY1 (0.68) | AHCYP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL10586180 | 0.91 | P2RY1 (0.68) | AHCYP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL18048495 | 0.90 | AHCY (0.57) | AHCYP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL1757017 | 0.89 | ADORA1 (0.73) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL9426538 | 0.89 | PRKACA (0.73) | AHCYP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL19859780 | 0.89 | ADORA1 (0.73) | P2RY1ADORA1SMN1; SMN2P2RY2SRC | |
| SCHEMBL2463542 | 0.89 | PRKACA (0.73) | AHCYP2RY1ADORA1SMN1; SMN2P2RY2 | |
| SCHEMBL6536155 | 0.89 | PRKACA (0.67) | AHCYP2RY1ADORA1SMN1; SMN2P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565646-A4 | — | — | 1994-08-03 | — | — | EP | disclosed |
| EP-0565646-A1 | NUCLEOSIDES AND OLIGONUCLEOSIDES WITH A PHOSPHATE-FREE INTERNUCLEOSIDE BACKBONE AND PROCESS FOR PREPARING THE SAME | BAYLOR COLLEGE OF MEDICINE (US) | 1993-10-20 | — | — | EP | disclosed |
| US-5175266-A | Oxidizing hydroxymethyl function of azidodeoxynucleosides to acid in presence of ruthenium tetroxide | TRIPLEX PHARMACEUTICAL CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| WO-1992018518-A1 | NUCLEOSIDES AND OLIGONUCLEOSIDES WITH A PHOSPHATE-FREE INTERNUCLEOSIDE BACKBONE AND PROCESS FOR PREPARING THE SAME | BAYLOR COLLEGE OF MEDICINE (US) | 1992-10-29 | — | — | WO | disclosed |