Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297212 | 0.97 | ESR1 (0.55) | ESR1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL9296385 | 0.86 | DGKA (0.49) | ESR1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL8555333 | 0.82 | ESR1 (0.59) | ESR1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL8468614 | 0.82 | ESR1 (0.59) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL17491352 | 0.81 | ESR1 (0.61) | ESR1DGKAAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9222985 | 0.81 | ESR1 (0.61) | ESR1DGKAAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL17491188 | 0.81 | ESR1 (0.61) | ESR1DGKAAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9230479 | 0.81 | ESR1 (0.61) | ESR1DGKAAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9225674 | 0.81 | ESR1 (0.61) | ESR1DGKAAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9228903 | 0.81 | ESR1 (0.61) | ESR1DGKAAKR1C4AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281570-A | Heat sensitive sheets | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-01-25 | — | — | US | disclosed |