Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 16/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 16/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989 | 0.79 | AGTR1 (0.40) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL22268662 | 0.77 | LTB4R2 (0.37) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL24355021 | 0.75 | DPP4 (0.50) | DPP8DPP7DPP4LTB4R2 | |
| SCHEMBL9430294 | 0.72 | AGTR1 (0.42) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9430054 | 0.72 | AGTR1 (0.41) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL9296080 | 0.71 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL1988 | 0.71 | LTB4R2 (0.56) | AGTR1LTB4R2 | |
| SCHEMBL1990 | 0.71 | LTB4R2 (0.56) | AGTR1LTB4R2 | |
| SCHEMBL9296071 | 0.71 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL3272 | 0.71 | LTB4R2 (0.56) | AGTR1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326776-A | Tetrazoles | ABBOTT LABORATORIES (US) | 1994-07-05 | — | — | US | disclosed |
| WO-1993017681-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |